Bimatoprost

  • CasNo:155206-00-1
  • 分子式:C25H37NO4
  • 纯度:99.0%MIN
  • 分子量:155206-00-1
询价

产品详情

Glaucoma medication
Bimatoprost is a synthetic prostaglandamide F2α derivative that selectively mimics the effects of prostacyclin produced in the body, increasing the rate of aqueous humor production, reducing the resistance to aqueous outflow, by increasing the trabecular meshwork and the uveoscleral membrane. The channel's aqueous outflow reduces intraocular pressure (IOP) and is considered to be the strongest local anti-glaucoma drug for ocular hypotensive. It is suitable for the treatment of open angle glaucoma (POAG) or other high intraocular pressure drugs. Patients with depression (OHT).

Certificate of analysis

 

Product Name

Bimatoprost

Batch No.

200601

Molecular Formula

C25H37NO4

CAS No.

155206-00-1

Manufacturing Date

2020.06.07

Retest Date

2022.06.06

Storage

Store a temperature below -15

Quality Specification

Enterprise Standard

Tests

Specifications

Results

Appearance

White or almost white powder

Conforms

Identification
NMR

Both spectrum of the test sample and the
reference standard exhibit the same
intensity of absorption at the same wave
number.

Conforms

Optical rotation

[α]2D0: +33.0°~+37.0°( c=1.0,CH3CN)

34.9°

Water

N.M.T.1.0 %

0.06%

Related Substances

5,6-trans-Bimatoprost and 15-keto-Bimatoprost:
N.M.T. 0.2 %
Any other unknown impurities: N.M.T. 0.10 %
Total impurities: N.M.T. 1.0%

0.03%
0.08%
0.26%

Residual solvents

Ethanol: N.M.T. 0.50%
Tert-Butyl methyl ether: N.M.T. 0.50%
Ethyl acetate: N.M.T. 0.50%

Not detected
Not detected
0.13%

Purity (HPLC)

N.L.T 99. 5%

99.74%

Conclusion

Conform to Enterprise Standard